Scientists from the University of Liverpool , ETH Zurich and Harvard Medical School have discovered additional benefits of the hypertension drug rilmenidine, such as delaying aging and extending life Oct. These findings were detailed in a study published in the journal Aging Cell. The study revealed that rilmenidine significantly extended life expectancy and improved health indicators in young and old animal models.
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How Does Rilmenidine Work?
Rilmenidine slows down the aging process by mimicking the effects of calorie restriction. Calorie restriction is known as one of the most effective methods of increasing longevity. However, it is difficult to apply in humans and may have side effects. Rilmenidine, on the other hand, mimics these effects in a similar way, offering an anti-aging solution.
In Research, C. in a roundworm model called elegans, rilmenidine treatment was shown to increase both healthy life expectancy and overall life expectancy through the I1-imidazoline receptor (nish-1). This finding suggests that the I1-imidazoline receptor may be a new target for anti-aging therapies.
The Mechanism of Operation of Rilmenidine: Structure that Mimics Calorie Restriction Rilmenidine slows down the aging process by mimicking the known benefits of calorie restriction. Calorie restriction is considered one of the most effective methods of increasing longevity in the scientific world. However, this method may be difficult to implement in humans and may have various side effects. Rilmenidine mimics the effects of calorie restriction in a similar way, offering an anti-aging solution and leading to minimal side effects in the process.
C. in experiments conducted on a roundworm model called elegans, it has been shown that rilmenidine prolongs life expectancy through the I1-imidazoline receptor (nish-1). These findings indicate that the I1-imidazoline receptor may be a new target in anti-aging therapies.
The Advantages of Rilmenidine
Rilmenidine is a widely prescribed antihypertensive, unlike other anti-aging drugs. The fact that the side effects are rare and mild increases the potential for this drug to be used safely in humans. This shows that rilmenidine is a promising option for delaying aging and extending life.
Safe Use as a Common Antihypertensive Rilmenidine, unlike other anti-aging drugs, is a widely prescribed antihypertensive drug. The fact that the side effects are rare and mild increases the potential for this drug to be used safely in humans. These properties indicate that rilmenidine is a promising option for delaying aging and extending lifespan. Anti-Aging Drugs of the Future Professor João Pedro Magalhães, who led the research, notes that with an aging population globally, the positive effects of delaying aging on health are great. Drugs such as rilmenidine have the potential to extend life expectancy and healthy life years. This study shows that rilmenidine can be used not only in the treatment of hypertension, but also as an anti-aging drug.
The Future of Anti-Aging Drugs
Professor João Pedro Magalhães, who led the research and is currently a fellow at the University of Birmingham, said: “With an ageing population globally, the benefits of delaying ageing are huge. Drugs such as rilmenidine have the potential to extend life expectancy and healthy life years,” he said.
This study shows that rilmenidine can be used not only in the treatment of hypertension, but also as an anti-aging drug. The researchers are continuing their work to explore other clinical applications of rilmenidine.
Anti-Aging Drugs of the Future Professor João Pedro Magalhães, who led the research, notes that with an aging population globally, the positive effects of delaying aging on health are great. Drugs such as rilmenidine have the potential to extend life expectancy and healthy life years. This study shows that rilmenidine can be used not only in the treatment of hypertension, but also as an anti-aging drug.
The Financing of the Study and the Supporting Institutions
This work was supported by prestigious institutions such as the Swiss National Science Foundation, LongeCity and the Biotechnology and Biological Sciences Research Council. These supports are critical for studying the effects of rilmenidine on aging in more depth, and also support research to explore other potential clinical applications of the drug. These findings show how rilmenidine can create a transformation in health sciences and offer new therapeutic avenues that can interfere with the aging process.
